International Cooperation for Post-Cherynobyl NIS Thyroid Tissue and Data Banks


Tracking Information

Start Date  ICMJEOctober 1999
Primary Completion Date 
Current Primary Outcome Measures  ICMJE 
Original Primary Outcome Measures  ICMJE 
 (submitted: October 19, 2007)
Antimullerian hormone, ovarian follicle count
Change HistoryComplete list of historical versions of study NCT00339274 on ClinicalTrials.gov Archive Site

Descriptive Information

Brief Title  ICMJEInternational Cooperation for Post-Cherynobyl NIS Thyroid Tissue and Data Banks
Official Title  ICMJEThe Chernobyl Tissue Bank
Brief Summary

The large number of thyroid tumors that have occurred in areas exposed to high levels of fallout from the Chernobyl accident raise problems of public health importance, or regulatory importance, and of scientific importance. The over-riding priority must go to matters such as diagnosis, treatment of those affected and prevention, and International Agencies are giving financial and material help in these areas. However providing the needs of the patient are not compromised, it is very important to ensure that information that may be of value to the health of future generations is not lost. International agencies are again providing financial support for a variety of joint studies, some of which are based on studies of tissues from thyroid operations carried out as part of treatment, and not required for the initial diagnosis on which treatment is based. An international coordinated approach to this problem is not in place to help Belarus, the Russian Federation and Ukraine to establish their own comprehensive thyroid tissue and data banks and to ensure that tissue and nucleic acids are used to contribute to the understanding of the consequences of the Chernobyl accident. This project has the support of the Governments of Belarus, the Russian Federation and Ukraine and the National Cancer Institute of the USA, (NCI), the European Commission (EC), the Sasakawa Memorial Health Foundation of Japan (SMHF) and the World Health Organization (WHO) have agreed to cooperate in supporting this project.

Detailed Description

The large number of thyroid tumors that have occurred in areas exposed to high levels of fallout from the Chernobyl accident raise problems of public health importance, or regulatory importance, and of scientific importance. The over-riding priority must go to matters such as diagnosis, treatment of those affected and prevention, and International Agencies are giving financial and material help in these areas. However providing the needs of the patient are not compromised, it is very important to ensure that information that may be of value to the health of future generations is not lost. International agencies are again providing financial support for a variety of joint studies, some of which are based on studies of tissues from thyroid operations carried out as part of treatment, and not required for the initial diagnosis on which treatment is based. An international coordinated approach to this problem is not in place to help Belarus, the Russian Federation and Ukraine to establish their own comprehensive thyroid tissue and data banks and to ensure that tissue and nucleic acids are used to contribute to the understanding of the consequences of the Chernobyl accident. This project has the support of the Governments of Belarus, the Russian Federation and Ukraine and the National Cancer Institute of the USA, (NCI), the European Commission (EC), the Sasakawa Memorial Health Foundation of Japan (SMHF) and the World Health Organization (WHO) have agreed to cooperate in supporting this project.

Study Phase 
Study Type  ICMJEObservational
Study Design  ICMJE 
Condition  ICMJEEnvironment
Intervention  ICMJE 

Recruitment Information

Estimated Enrollment  ICMJE4000
Completion Date 
Primary Completion Date 
Eligibility Criteria  ICMJE
  • INCLUSION CRITERIA:

Patients with thyroid tumours from the whole of Belarus, and the contaminated oblasts of the Russian Federation and Ukraine who were born after 26th April 1967.

GenderBoth
Ages 
Accepts Healthy VolunteersNo
Contacts  ICMJE
Contact: Geraldine Thomas, Ph.D.441223740181gerry@mynydd-p.u-net.com
Location Countries  ICMJEBelarus,   Japan,   Russian Federation,   Ukraine,   United Kingdom

Administrative Information

NCT ID  ICMJENCT00339274
Responsible Party 
Study ID Numbers  ICMJE999900024, OH00-C-N024
Study Sponsor  ICMJENational Cancer Institute (NCI)
Collaborators  ICMJE 
Investigators  ICMJE 
Information Provided ByNational Institutes of Health Clinical Center (CC)